Celery seeds are a great source of magnesium, with one tablespoon (6.5 grams) providing 12% of the RDI. In Asian medicine, celery seed is used to treat headaches and as a diuretic, digestive aid, and emmenagogue. Coronary heart disease is the leading cause of death in many countries. Boffa, M. J., Gilmour, E., and Ead, R. D. Celery soup causing severe phototoxicity during PUVA therapy. One tablespoon (6.5 grams) of the seeds packs an impressive 27% of the RDI. Effects of aqueous celery (Apium graveolens) extract on lipid parameters of rats fed a high fat diet. Crossed or concomitant allergy?]. WebJust eating celery wont have the same effect. Discover essential oils that can aid in reducing gout symptoms. 2006;44(9):1474-1484. J Toxicol.Clin Toxicol. Yusni Y, Zufry H, Meutia F, Sucipto KW. A handful of celery seeds will help cleanse your urinary tract and keep it void of any unwanted bacteria. 2023 Healthline Media LLC. This information is not specific medical advice and does not replace information you receive from your health care provider. Unsurprisingly, the flavor of celery seed resembles that of a celery stalk. The celery plant is slender and stands about 2 to 3 feet tall. Ahmed B, Alam T, Varshney M, Khan SA. In short, celery is a plant based alternative to preserving and curing organic meat and other products. Br J Dermatol. But more importantly, they contain components that induce apoptosis, which causes cancer cells to self-destruct (x). New York Eye and Ear Infirmary of Mount Sinai, The Blavatnik Family Chelsea Medical Center, Heart - Cardiology and Cardiovascular Surgery, Mount Sinai Center for Asian Equity and Professional Development, Preparing for Surgery and Major Procedures, Herbs with Similar Side Effects as: Celery Seed, Herbs with Similar Warnings as: Celery Seed, Flavonoids, which are antioxidants that give plants their colors and may protect cells from damage, Coumarins, chemicals that help thin the blood. Other reactions that can result from handling the plant or eating large amounts of celery seeds include tiredness, slowed breathing and decreased heartbeat, warns Summit Medical Group. 1995;49:119-126. Eastern medicine has used celery seeds for thousands of years to treat ailments like bronchitis, skin disorders, and the flu (1). In about 450 BC, the Greeks used celery to make a type of wine called selinites, which was given as an award at early athletic games, much like laurel leaves or olive branches. Celery seeds consist of the oil (petroselinic, linoleic, palmitic, and oleic fatty acids) and volatile compounds, mostly monoterpene hydrocarbons.Kooti 2017 The major WebOf these, 3-n-butylphthalide (3nB) is one of the most well researched. Tsi D, Das NP, Tan BK. Food Chem.Toxicol. Celery seeds are rich in many essential nutrients for bone health like calcium, manganese, magnesium, and phosphorus. Furthermore, celery actively boosts digestion, relieves bloating and treats water retention. Ding Y, et al. For these reasons, you should only take celery seed supplements under the supervision of a health care provider. For this reason, it is important to consult with your healthcare provider before taking supplemental celery seed. Here are five reasons you should consider adding celery to your diet. Based on the positive results in this small pilot study, a larger 70-patient study was conducted. DOI: Vieira AT, et al. Rouhi-Boroujeni H, Hosseini M, Gharipour M, Rouhi-Boroujeni H. Is herbal therapy safe in obesity? Almost 70% of older adults use them. However, various research studies may give us a starting place for beneficial dosages in humans. Celery stalks and celery juice are a healthy food choice, but they dont contain as many of the beneficial compounds as the seeds and oil. Gorgus, E., Lohr, C., Raquet, N., Guth, S., and Schrenk, D. Limettin and furocoumarins in beverages containing citrus juices or extracts. Maso, M. J., Ruszkowski, A. M., Bauerle, J., DeLeo, V. A., and Gasparro, F. P. Celery phytophotodermatitis in a chef. Fraser L and et al. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. Sarshar S, Sendker J, Qin X, et al. Many delicious ingredients are also exceptionally healthy. Gral N, Beani JC, Bonnot D, et al. Use sunscreen or sunblock lotions. A new French multicenter study]. Web1) celery seed extract (tried this after using celery seed on its own to no success) 2) sunflower lecithin. A novel compound from celery seed with a bactericidal effect against Helicobacter pylori. Celery seed is contraindicated in pregnancy. 2004;98(4):407-17. Talk with your healthcare provider before using celery if you are taking lithium. For example, theyre a great source of essential minerals like calcium, manganese, and iron. Total venlafaxine and metabolite levels were elevated, and serotonin syndrome was ruled out. Researchers have found that people who eat a diet rich in lutein, found in celery, spinach, broccoli, lettuce, tomatoes, oranges, carrots, and greens, were less likely to develop colorectal cancer. View abstract. Eur.J Drug Metab Pharmacokinet. Apiole has been used for centuries as an abortifacient: an herb used to cause a deliberate miscarriage. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. Furthermore, consuming celery seed extract with a balanced diet plan could help to manage overall cholesterol levels. This could change the effects and side effects of these medications. Forsbeck, M. and Ros, A. M. Anaphylactoid reaction to celery. All rights reserved. 2010;65(6):792-3. WebMany subjects noticed the celery seed extract produced a diuretic effect, but no changes were noted in their sodium and potassium balances. Gout is a chronic inflammatory condition marked by the buildup and crystallization of uric acid in the joints and tissues. View abstract. View abstract. To establish that the product manufacturers addressed safety and efficacy standards, we: We do the research so you can find trusted products for your health and wellness. (Paris) 1995;27(3):91-93. DOI: Dolati K, et al. This could make the effects of blood thinners stronger and raise the risk of bleeding. Rose, M. H. and Altman, L. C. Anaphylaxis after ingestion of raw celery. Paul Pitchford, in his book "Healing with Whole Foods," recommends celery juice combined with lemon juice to treat headaches caused by high blood pressure and excessive heat. Reductions in plasma glucose levels were reported, but not in plasma insulin levels.Yusni 2018, A protective effect of celery leaves and seeds on gastric ulceration has been demonstrated in studies of rats.Al-Howiriny 2010, Baananou 2013, Hydroalcoholic extracts of whole A. graveolens plant may have a role in the management of gout, based on reduced serum uric acid levels in a study of rodents with induced hyperuricemia. Data sources include IBM Watson Micromedex (updated 1 May 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. See additional information. 2018;127:237-244. If you experience any of the following symptoms, get immediate medical attention: Before taking a supplement containing celery seed extract, ask your doctor if you are on any medication that may interact with the herb. Atta AH, Alkofahi A. Anti-nociceptive and anti-inflammatory effects of some Jordanian medicinal plant extracts. 2005;221(1):11-20. View abstract. Allergy 1997;52(4):428-431. But only about 25% of people who take herbal supplements tell their health care providers. Hoerler, S. and Ukiwe, J. Laryngeal edema from celery allergic reaction. There are a handful of other compounds in celery seed that may exhibit other antioxidant and anti-inflammatory properties. 2003;41:235-239. Here are 6 surprising benefits of celery seeds. Here are a few recommendations for celery seed supplements that might be beneficial for gout, although you should speak with your doctor first: Natural Factors J AOAC Int 2001;84(4):1135-1143. Celery is a popular vegetable, but theres more to this plant than the stalk alone. A number of celery varieties exist, many of which are developed to meet commercial demands for particular colors, tastes, and stalk sizes. 2021;2021:5589597. From lowering blood pressure to fighting inflammation and treating infections, celery seeds offer a multitude of health benefits. 1985;3:85. Celery stem, oil, and seeds are commonly consumed in foods. Cancer Lett. 2018;39(2):154-160. Treatment of women's sexual dysfunction using Apium graveolens L. Fruit (celery seed): a double-blind, randomized, placebo-controlled clinical trial. 3) pygeum. Celery seed contains compounds that may be beneficial in the treatment of gout. celery seed extract, fresh or dried seeds, tablets and as capsules filled with celery seed oil. Helps maintain already-normal blood pressure*. Select a condition to view a list of vitamins. 1994;130(6):809-810. The seed is used as a spice. View abstract. In many countries, celery is harvested primarily for its seeds due to the medicinal properties they contain. Current research on celery seed has shown benefits at the following dosages: Research studies on celery seed, like many botanical medicine studies, primarily use hydroalcoholic extracts. DOI: Bakar FIA, et al. Severe phototoxic burn following celery ingestion. Ned.Tijdschr.Geneeskd. Some medications are changed and broken down by the liver. However, more research is required to verify this effect of celery in humans. View abstract. Evidence from a preliminary study in Natural Medicine Journal in April 2013 indicated that celery seed extract may decrease both systolic and diastolic blood pressure. Taking celery root extract with venlafaxine might increase the effects and side effects of venlafaxine. The most common location of gout pain is the large toe, although it can occur in other joints too. Part 182 -- Substances Generally Recognized As Safe. Can drinking this bright green juice really give your body a healthy boost? Tuetun, B., Choochote, W., Pongpaibul, Y., Junkum, A., Kanjanapothi, D., Chaithong, U., Jitpakdi, A., Riyong, D., and Pitasawat, B. Celery-based topical repellents as a potential natural alternative for personal protection against mosquitoes. The most notable compounds in celery seed include: These compounds have been researched for their role in inflammation and uric acid production, which is a driving force behind the severity of gout attacks. Postepy Hig Med Dosw (Online). Zhou Y, Taylor B, Smith TJ, Liu ZP, Clench M, Davies NW, Rainsford KD. Some studies have suggested it may modestly improve blood pressure, cholesterol, and C-reactive protein Trop.Med Int Health 2005;10(11):1190-1198. Further studies are needed to confirm these results so, to play it safe, monitor your blood pressure if you are taking a celery supplement. Allergy, including dermatitis and anaphylaxis (rare), to celery and its constituents has been reported, as has phototoxicity. A study in Preventive Medicine and Food Science, published in June 2018, investigated the effect of celery and its hydroalcoholic extracts on the treatment of gout. Jeanmougin, M., Varroud-Vial, C., and Dubertret, L. [Phototoxic side-effect following celery ingestion during puvatherapy]. WebMy recommendation is to either consume eight ribs of celery per day or take a celery seed extract standardized to contain 85 percent 3nB and other celery phthalides at a dosage One tablespoon (6.5 grams) of celery seeds provides (2): Celery seeds are low in calories, with a tablespoon providing about 25 calories. View abstract. View abstract. Nutr Cancer. Sohrabi F, Niazmand S, Mahmoudabady M, Niazmand MJ. Allergy 2001;56(1):82-83. Hepatoprotective activity of two plants belonging to the Apiaceae and the Euphorbiaceae family. CONDITIONS OF USE AND IMPORTANT INFORMATION: This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. 2000;57(13):1221-1227. A review of the antioxidant activity of celery (. However, herbs can have side effects and interact with other herbs, supplements, or medications. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. in blood pressure. A common dietary herbal intervention for gout is celery. If you have a history of heart disease, you may want to start with a lower dose of the herb. All rights reserved. Springhouse, PA: Springhouse Corp., 1999. Healthline only shows you brands and products that we stand behind. WebDose: to 5/8 tsp whole celery seeds, chewed/ground, with breakfast Effect on Cum Volume: Solid increase (~11%) Effect on Sperm Volume: Significant increase (~26%) Effect on Libido: Solid increase, on average, but this effect proved uneven; erections come easier and View abstract. 1998;60:117-124. Do not use celery seed or apply celery seed oil if you are in the sun for an extended period of time. The essential oil produces sedative effects. As always, its important to consult your doctor before starting a new herbal supplement. Celery seed has "generally recognized as safe" (GRAS) status when used as a food, according to the US Food and Drug Administration (FDA). Celery seeds are a versatile spice. Inhibition of cell adhesion, antiangiogenic properties, proapoptosis, and other effects have been demonstrated in studies using human cancer cell lines.Iyer 2019, Kasiri 2018, Kowalczyk 2017, Sung 2016 In vitro and rodent studies suggest essential oil from celery may also possess cytotoxic and antimutagenic properties.Christensen 2006, Hashim 1994, Lim 2013, Zheng 1993, Celery extract has demonstrated vasorelaxant effects on isolated rat aortic rings.Jorge 2013 Celery seed extract exerted hypotensive effects in hypertensive, but not normotensive, rats, possibly due to the n-butylphthalide content.Moghadam 2013, Tang 2017 Limited studies in rodents report improved lipid profiles with celery seed extracts.Abd El-Mageed 2011, Iyer 2011, Iyer 2019, Rouhi-Boroujeni 2015 Additional effects in cardiovascular disease include decreased secretion of proinflammatory cytokines.Tang 2017, Limited clinical studies have been conducted to evaluate the effects of the extracted compound butylphthalide in strokeWang 2018; one study demonstrated superiority of 90-day treatment with dl-3-n-butylphthalide (a synthetic variation of l-3-n-butylphthalide, an extract from seeds of A. graveolens) over aspirin in patients with acute ischemic stroke.Cui 2013 The synthetic version of the compound is clinically approved as an anti-ischemic agent in China.Abdoulaye 2016, In older studies, 3-n-butylphthalide showed sedative and anticonvulsant effects in rodents.Khan 2009 In induced Parkinson disease models in mice, extracts from whole A. graveolens plant improved behavioral performance, oxidative stress parameters, and monoamine oxidase A and B activity.Chonpathompikunlert 2018, Huang 2010 Other studies in rodents report improvements in cognition and depression, and modulation of endogenous antioxidant and neurotransmitter systems.Boonruamkae 2017 Reviews exist regarding neuroprotective effects of the flavone luteolin, which is found in several plant products, including celery.Nabavi 2015, Clinical studies are lacking. Be that as it may, you should consult a physician before adding celery seed extract to your daily routine. Your lithium dose might need to be changed. However, theyre also available as a supplement in extract or capsule form. So it could make the effects of other diuretics stronger and raise the risk of dehydration. Bauer L, Ebner C, Hirschwehr R, et al. Teng CM, Lee LG, Ko SN, et al. Experts advise against using celery seed supplements if youre pregnant, as it may cause uterine bleeding and even miscarriage (32, 33). Anti-gout potential of Malaysian medicinal plants. Along with a healthy diet, seeds can help reduce blood sugar, cholesterol and blood pressure. Gout is triggered when uric acid builds up within the joints. This product may be unsafe when used before surgery or other medical procedures. DeChamp, C., Michel, J., Deviller, P., and Perrin, L. F. [Anaphylactic shock to celery and sensitization to ragweed and mugwort. Maljaei MB, Moosavian SP, Mirmosayyeb O, Rouhani MH, Namjoo I, Bahreini A. But again, researchers do not know whether those effects apply to humans. This item: Celery Seed Extract by Natural Factors, Herbal Supplement for a Healthy Circulatory System, 120 Capsules $25.17 ($0.21/Count) Olive Leaf Extract (Non-GMO) Super Strength: 20% Oleuropein - 750mg - Vegetarian - Immune Support Supplement, Skin Health, and Powerful Antioxidants Supplement - No Oil or Liquid - 60 Asia Pac J Pharmacol. Mice that were given celery seed extract showed a significant reduction in total cholesterol, triglycerides and low-density lipo-protein cholesterol (x). View abstract. This helps your blood vessels to expand and facilitates the smooth circulation of blood and, thus, reduces blood pressure. WebOral administration of celery seed extract (300 mg/kg) for six weeks prevented an increase in oxidative stress and hepatic enzyme and bilirubin levels. It contains allergens that may provoke severe allergic reactions, including anaphylaxis, reports the 2017 Pharmacognosy Review study. Am J Health Syst Pharm. celery seed extract in 1,000 mg increments once to three times daily, or as Diuretics (water pills): Celery seed acts as a diuretic. Celery seeds contain many of these important nutrients. Celery seeds are a great source of non-heme iron. Some medications might make the skin more sensitive to sunlight. In one in vitro study, it was revealed that luteolin is one of the flavonoids that can inhibit xanthine oxidase. This information should not be used to decide whether or not to take this product. Some of these include lithium, diuretics, anticoagulants and thyroid medications, according to Penn State Hershey. Heck AM, DeWitt BA, Lukes AL. Rich in Important Nutrients. View abstract. View abstract. Advertisement references Thyroid medications: Celery seed may interact with thyroid medications. Eating iron-rich food helps your body produce red blood cells and may prevent anemia. Saudi Med J. Scientific Name(s): Apium graveolens L. var dulce (Mill.) These seeds have usually been treated with chemicals. View abstract. A small study in elderly patients with hyperglycemia (N=16) evaluated the effect of celery leaf on blood glucose and plasma insulin levels. Al-Asmari AK, et al. Celery seeds are a great source of iron for both men and women. Their flavor is warm and bitter. Miller L. Herbal medicinals: selected clinical considerations focusing on known or potential drug-herb interactions. Celery seeds are nutrient dense and particularly rich in calcium, manganese, and iron. Celery root extract might decrease how quickly the body breaks down venlafaxine. BuPh, or 3-n-butylphthalide, is a compound present in celery that improves heart health due to its lipid-lowering capabilities. Hirschfeld G, Weber L, Renkl A, Scharffetter-Kochanek K, Weiss JM. Theyre particularly rich in various minerals, such as calcium, iron, and manganese. Celery seeds consist of the oil (petroselinic, linoleic, palmitic, and oleic fatty acids) and volatile compounds, mostly monoterpene hydrocarbons.Kooti 2017 The major constituents of celery seed oil are d-limonene (60%), selinene (10%), and related phthalides (3%) (eg, 3-n-butylphthalide, sedanenolide, sedanonic anhydride). Celery has shown promise as a natural therapy for these and other health issues in animal studies, but remains to be proven effective in humans. Through dietary interventions, you may be able to reduce the levels of uric acid in the blood and minimize painful flare-ups. 6-20-1992;136(25):1210-1213. Its most active chemical, curcumin, has potent anti-inflammatory and antioxidant properties. Celery has also been prescribed as an antiflatulent, antilactogen, and aphrodisiac.Al-Asmari 2017, Bisset 1994, Garfield 1985, The celery leafstalk is high in minerals, including sodium, potassium, calcium, magnesium, and iron and nitrates; however, it is a relatively poor source of vitamins except for vitamin C.Afourtit 2015, Meng-Yao 2018. Heck AM, DeWitt BA, Lukes AL. J Ethnopharmacol. The dosage Dermatol Ther 2004;17(4):279-288. -selinene-rich essential oils from the parts of. (2019). Although herbal remedies are generally accepted as complementary and alternative therapies in combination with other medications, herbs can have side effects and interact with other herbs, supplements and medications. Here are a few more ways to add celery seeds to your diet: Interestingly, some people use ground celery seed to make tea. Last updated on May 23, 2022. View abstract. Br.J.Dermatol. Celery seed extract is linked to 0 conditions and outcomes. More n Vito research is needed to verify these preliminary findings. One tablespoon (6.5 grams) of celery seeds provides ( 2 Trusted Source ): 1 Calories: 25 calories 2 Carbs: 2 grams 3 Protein: 1 gram 4 Fat: 2 grams 5 Fiber: 1 gram 6 Calcium: 12% of the Reference Daily Intake (RDI) 7 Zinc: 6% of the RDI 8 Manganese: 27% of the RDI 9 Iron: 17% of the RDI 10 Magnesium: 9% of the RDI More items Celery is commonly consumed as a vegetable and its components such as seeds are commonly used as a food seasoning ingredient. However, more research in humans is needed. Your body requires a healthy balance of antioxidants and free radicals to maintain optimal health (28). Celery seeds contain methanolic and hexane extracts, which help with circulation. Our website services, content, and products are for informational purposes only. Cheung MC, Lin LY, Yu TH, Peng RY. Peterson, S., Lampe, J. W., Bammler, T. K., Gross-Steinmeyer, K., and Eaton, D. L. Apiaceous vegetable constituents inhibit human cytochrome P-450 1A2 (hCYP1A2) activity and hCYP1A2-mediated mutagenicity of aflatoxin B1. Wild celery can refer to Vallisneria spiralis L., an aquatic perennial. Health 1992;6(5):11. Indeed, celery seed is a natural alternative to synthetic repellents for protection against mosquitoes. Ann.Gastroenterol Hepatol (Paris) 1995;31(4):256-263. Consider therapy modification.Mousa 2010, Spolarilch 2007, Stanger 2012, Ulbricht 2008, Hypoglycemia-associated agents: Herbs (hypoglycemic properties) may enhance the hypoglycemic effect of hypoglycemia-associated agents. The Department of Pharmacology at the University of Singapore put mice on a high-fat diet for eight weeks. Including magnesium-rich foods like celery seeds in your diet may reduce your risk of type 2 diabetes. Celery seeds contain non-heme iron. Celery extract replenishes lost levels of gastric mucus, keeping small holes and openings from damaging the lining of the digestive tract (x). Luteolin may reduce uric acid levels and reduce inflammatory nitric oxide production. This may lead to a lower bone mineral density, which is a measure of the number of minerals present in a certain volume of bone (3, 4, 5). People with low blood sugar, acute kidney inflammation, or an allergy to celery seeds or birch pollen should also avoid taking celery seed (34). Herbal infusions used for induced abortion. Celery is a biennial plant that was first cultivated in Europe but is grown and consumed worldwide. One common dietary intervention for gout is celery. Blood-thinning medications (anticoagulants and antiplatelets): Celery seed contains chemicals that may thin the blood. This is only a brief summary of general information about this product. Am Fam.Physician 1989;39(4):143-146. One tablespoon (6.5 grams) of celery seeds provides 17% and 38% of the RDIs for women and men, respectively. Bleeding may occur. A tablespoon of celery seed contains 17 percent of the recommended daily value of iron, which is a significant boost for at-risk groups or those looking to increase their hemoglobin levels. It can even increase the secretion of testosterone ( 24 ). Today, celery seed is used mostly as a diuretic, meaning it helps your body eliminate water by increasing urine output. Celery generally grows to between 0.3 m and 0.6 m in height. DO NOT take celery seeds from a gardening packet. DOI: Pauff JM, et al. 10 Facts You Need to Know About Food Allergies, Penn State Hershey Medical Center: "Celery Seed", Journal of Drug Discovery and Therapeutics: "Medical Benefits of Apium Graveolens (Celery Herb", Preventive Medicine and Food Science: "Inhibitory Effects of Apium graveolens on Xanthine Oxidase Activity and Serum Uric Acid Levels in Hyperuricemic Mice", Pharmacognosy Review: "An Updated Phytopharmacological Review on Medicinal Plant of Arab Region: Apium Graveolens Linn", Natural Medicine Journal: "A Pilot Study to Evaluate the Antihypertensive Effect of a Celery Extract in Mild to Moderate Hypertensive Patients", American Academy of Allergy, Asthma, Immunology: "Allergy to Celery", University of Nebraska - Lincoln: Food Allergy Research and Resource Program: "Allergenic Foods and their Allergens, with links to Informall", A swollen throat or the constriction